Adenosine Dialdehyde (ADOX) Snap

Adenosine Dialdehyde (ADOX) SnapAdenosine Dialdehyde (ADOX) is an adenosine analog and S adenosylmethionine dependent methyltransferase inhibitor with an IC50 of 40 nM.

Molidustat (BAY 85-3934) is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor with IC50 of 480 nM

BH3I-1 is a Bcl-XL-BH3 domain interaction inhibitor with Ki of 2

Its lid is partly made of glass therefore the operator can observe the filter and make sure that it remains in the same position after chamber closing

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays

selective histamine H1 receptor antagonist with anti-allergic activity

and inhibits FKBP-12 binding with IC50 of 2

6/Case - COP

Taladegib (LY2940680) binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling

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It activates AMPK

It is more than 8-fold selective for Aurora A/B than MEK1

non-optical